Lower serum branched-chain amino acid catabolic intermediates are predictive signatures specific to patients with diabetic foot

• Published in: Nutrition research (New York, N.Y.) Vol. 119; pp. 33 - 42
• Main Authors: Wang, Tao, Wang, Mingbang, Liu, Liming, Xie, Fang, Wu, Xuanqin, Li, Liang, Ji, Jun, Wu, Dafang
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.11.2023
• Subjects: Branched chain amino acid catabolic pathways; Diabetic foot; Metabolic markers; MMA; T2DM; DF; POA; KetoLeu; 3M2OxoValA; BCKA; AUROC; POA_ISO; Metabolic markers; SA; ARA; LC-MS/MS; DPA; Diabetic foot; T2DM-F; hsCRP; Branched chain amino acid catabolic pathways; HC; DHA; BCAA

Diabetic foot (DF) is one of the serious chronic complications of diabetes. Accurate prediction of the risk of DF may take timely intervention measures to prevent its occurrence. The understanding of metabolomic changes in the progression of diabetes to DF may reveal new targets for interventions. W...