Molecular evolution and regulation of DHN melanin-related gene clusters are closely related to adaptation of different melanin-producing fungi

• Published in: Genomics (San Diego, Calif.) Vol. 113; no. 4; pp. 1962 - 1975
• Main Authors: Jia, Shu-Lei, Chi, Zhe, Chen, Lu, Liu, Guang-Lei, Hu, Zhong, Chi, Zhen-Ming
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2021
• Subjects: Aspergillus; Aspergillus/Penicillium spp; Aureobasidium melanogenum; biosynthesis; Co-evolution; coevolution; DHN melanin-related gene clusters; Divergence time; Evolution, Molecular; Fungi - genetics; Gene Transfer, Horizontal; genes; genomics; horizontal gene transfer; melanin; Melanins - genetics; Multigene Family; Penicillium; species; Divergence time; Aureobasidium melanogenum; Co-evolution; Aspergillus/Penicillium spp; DHN melanin-related gene clusters

Many genes responsible for melanin biosynthesis in fungi were physically linked together. The PKS gene clusters in most of the melanin-producing fungi were regulated by the Cmr1. It was found that a close rearrangement of the PKS gene clusters had evolved in most of the melanin-producing fungi and v...