A possible role for G-quadruplexes formation and DNA methylation at IMOOD gene promoter in Obsessive Compulsive Disorder

• Published in: Advances in biological regulation Vol. 89; p. 100976
• Main Authors: Sabatucci, Annalaura, Girella, Antonio, Di Bartolomeo, Martina, Pucci, Mariangela, Vismara, Matteo, Benatti, Beatrice, Blacksell, Isobel Alice, Cooper, Dianne, Dainese, Enrico, D'Acquisto, Fulvio, Dell’Osso, Bernardo, D'Addario, Claudio
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2023
• Subjects: DNA methylation; G-quadruplex; IMOOD; OCD molecular markers; OCD molecular markers; IMOOD; DNA methylation; G-quadruplex

Obsessive Compulsive Disorder (OCD) is a mental health condition still classified and diagnosed with subjective interview-based assessments and which molecular clues have not completely been elucidated. We have recently identified a new regulator of anxiety and OCD-like behavior called Immuno-moodul...