mtDNA mutations in human aging and longevity: Controversies and new perspectives opened by high-throughput technologies - Sevini, Federica; Giuliani, Cristina; Vianello, Dario; Giampieri, Enrico; Santoro, Aurelia; Biondi, Fiammetta; Garagnani, Paolo; Passarino, Giuseppe; Luiselli, Donata; Capri, Miriam; Franceschi, Claudio; Salvioli, Stefano (Experimental gerontology, 2014)
Keywords: Age Factors; Aging - genetics; Aging - metabolism; Computational Biology; DNA Damage; DNA Mutational Analysis; DNA, Mitochondrial - genetics; DNA, Mitochondrial - metabolism; Epigenesis, Genetic; Epistasis; Gene Expression Regulation; Genotype; Heteroplasmy; High-Throughput Nucleotide Sequencing - methods; Humans; Longevity; Longevity - genetics; Mitochondrial DNA; mtDNA mutations; Mutation; Next generation sequencing; Phenotype; GWAS; mtDNA; OXPHOS; mtDNA mutations; Mitochondrial DNA; Epistasis; Longevity; Next generation sequencing; polγ; Heteroplasmy; GEHA; ROS; 90; nDNA; NGS