Role of subject-specific musculoskeletal loading on the prediction of bone density distribution in the proximal femur

• Published in: Journal of the mechanical behavior of biomedical materials Vol. 30; pp. 244 - 252
• Main Authors: Vahdati, A., Walscharts, S., Jonkers, I., Garcia-Aznar, J.M., Vander Sloten, J., van Lenthe, G.H.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.02.2014
• Subjects: Adult; Bone Density; Bone density prediction; Bone Remodeling; Bones; Computational bone remodeling; Density; Density distribution; Female; Femur; Femur - physiology; Finite Element Analysis; Gait analysis; Humans; Male; Mathematical models; Middle Aged; Models, Biological; Muscles; Musculoskeletal modeling; Proximal femur; Remodeling; Subject-specific simulation; Surgical implants; Weight-Bearing; Computational bone remodeling; Musculoskeletal modeling; Subject-specific simulation; Proximal femur; Bone density prediction; Gait analysis

The typical bone density patterns in the proximal femur can be explained using bone remodeling simulations incorporating a load-adaptive response. Yet, subject-specific variations in bone density have not received much attention. Therefore, the objective of this study was to quantify to what extent...