TDCS increases cortical excitability: Direct evidence from TMS–EEG

• Published in: Cortex Vol. 58; pp. 99 - 111
• Main Authors: Romero Lauro, Leonor J., Rosanova, Mario, Mattavelli, Giulia, Convento, Silvia, Pisoni, Alberto, Opitz, Alexander, Bolognini, Nadia, Vallar, Giuseppe
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.09.2014; Elsevier
• Subjects: Adult; Anatomical correlates of behavior; Behavioral psychophysiology; Biological and medical sciences; Cortical excitability; Electroencephalography; Evoked Potentials, Motor - physiology; Female; Fundamental and applied biological sciences. Psychology; Humans; Male; Motor Cortex - physiology; Parietal Lobe - physiology; Posterior parietal cortex; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; tDCS; TMS-EEG; Transcranial Magnetic Stimulation; Young Adult; Cortical excitability; TMS-EEG; tDCS; Posterior parietal cortex; Human; Cerebral cortex; Central nervous system; Electrophysiology; Electroencephalography; Experimental study; Transcranial direct current stimulation; Transcranial electrical stimulation; Encephalon; Parietal cortex

Despite transcranial direct current stimulation (tDCS) is increasingly used in experimental and clinical settings, its precise mechanisms of action remain largely unknown. At a neuronal level, tDCS modulates the resting membrane potential in a polarity-dependent fashion: anodal stimulation increases...