Transmural Wave Speed Gradient May Distinguish Intrinsic Myocardial Stiffening from Preload-Induced Changes in Operational Stiffness in Shear Wave Elastography

• Published in: IEEE transactions on biomedical engineering Vol. 70; no. 1; pp. 1 - 12
• Main Authors: Caenen, Annette, Bezy, Stephanie, Petrescu, Aniela, Werner, Annegret, Voigt, Jens-Uwe, Dhooge, Jan, Segers, Patrick
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.01.2023; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Cardiac shear wave elastography; Computational modeling; Data analysis; Elasticity Imaging Techniques - methods; Finite element analysis; Finite element method; finite element model; Heart - diagnostic imaging; hemodynamic loading; Hemodynamics; Humans; intrinsic stiffness; Load modeling; Microsurgery; Myocardium; operational stiffness; Pressure; Propagation; Shear; Solid modeling; Stiffening; Stiffness; Strain; Ventricle; Wave physics; Wave propagation

Background : Shear wave elastography (SWE) is a promising technique to non-invasively assess myocardial stiffness based on the propagation speed of mechanical waves. However, a high wave propagation speed can either be attributed to an elevated intrinsic myocardial stiffness or to a preload-induced...