Metal‐Free Visible‐Light Promoted Radical Cyclization to Access Perfluoroalkyl‐Substituted Benzimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and Indolo[2,1‐a]isoquinolin‐6(5H)‐ones

• Published in: Advanced synthesis & catalysis Vol. 361; no. 22; pp. 5176 - 5181
• Main Authors: Zeng, Fan‐Lin, Sun, Kai, Chen, Xiao‐Lan, Yuan, Xiao‐Ya, He, Shuai‐Qi, Liu, Yan, Peng, Yu‐Yu, Qu, Ling‐Bo, Lv, Qi‐Yan, Yu, Bing
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 19.11.2019
• Subjects: Chemistry; Chemistry, Applied; Chemistry, Organic; Metal free; Perfluoroalkylation; Photocatalyst free; Physical Sciences; Radical cascade reaction; Science & Technology; Visible-light; COMPLEX; CASCADE; IONIC LIQUID; Visible-light; CATALYST; FUNCTIONALIZATION; IRRADIATION; ALKENES; Perfluoroalkylation; CONDENSATION; Radical cascade reaction; QUINOXALIN-2(1H)-ONES; Photocatalyst free; Metal free; N-HETEROCYCLES

A metal‐free visible‐light‐induced cyclization procedure was developed for the rapid synthesis of perfluoroalkyl‐substituted benzimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and perfluoroalkyl‐substituted indolo[2,1‐a]isoquinolin‐6(5H)‐ones under mild reaction conditions. In this procedure, the formation of...