Metal‐Free Visible‐Light Promoted Radical Cyclization to Access Perfluoroalkyl‐Substituted Benzimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and Indolo[2,1‐a]isoquinolin‐6(5H)‐ones

A metal‐free visible‐light‐induced cyclization procedure was developed for the rapid synthesis of perfluoroalkyl‐substituted benzimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and perfluoroalkyl‐substituted indolo[2,1‐a]isoquinolin‐6(5H)‐ones under mild reaction conditions. In this procedure, the formation of...

Full description

Saved in:
Bibliographic Details
Published inAdvanced synthesis & catalysis Vol. 361; no. 22; pp. 5176 - 5181
Main Authors Zeng, Fan‐Lin, Sun, Kai, Chen, Xiao‐Lan, Yuan, Xiao‐Ya, He, Shuai‐Qi, Liu, Yan, Peng, Yu‐Yu, Qu, Ling‐Bo, Lv, Qi‐Yan, Yu, Bing
Format Journal Article
LanguageEnglish
Published WEINHEIM Wiley 19.11.2019
Subjects
Chemistry
Chemistry, Applied
Chemistry, Organic
Metal free
Perfluoroalkylation
Photocatalyst free
Physical Sciences
Radical cascade reaction
Science & Technology
Visible-light
COMPLEX
CASCADE
IONIC LIQUID
Visible-light
CATALYST
FUNCTIONALIZATION
IRRADIATION
ALKENES
Perfluoroalkylation
CONDENSATION
Radical cascade reaction
QUINOXALIN-2(1H)-ONES
Photocatalyst free
Metal free
N-HETEROCYCLES
Online AccessGet full text

Cover

More Information
Summary:A metal‐free visible‐light‐induced cyclization procedure was developed for the rapid synthesis of perfluoroalkyl‐substituted benzimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and perfluoroalkyl‐substituted indolo[2,1‐a]isoquinolin‐6(5H)‐ones under mild reaction conditions. In this procedure, the formation of electron‐donor‐acceptor (EDA) complex is critical for the visible‐light promoted process to avoid the utilization of external photocatalysts.
Bibliography:Fan‐Lin Zeng and Kai Sun contributed equally
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.201901016