Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case-control study

• Published in: Journal of hypertension Vol. 24; no. 3; p. 581
• Main Authors: Rejnmark, Lars, Vestergaard, Peter, Mosekilde, Leif
• Format: Journal Article
• Language: English
• Published: England 01.03.2006
• Subjects: Adolescent; Adrenergic beta-Antagonists - therapeutic use; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Bone and Bones - drug effects; Calcium Channel Blockers - pharmacology; Calcium Channel Blockers - therapeutic use; Case-Control Studies; Female; Fractures, Bone - epidemiology; Fractures, Bone - prevention & control; Humans; Male; Middle Aged; Odds Ratio; Risk Assessment

Cardiovascular diseases are associated with disturbances in calcium metabolism, including increased urinary calcium, vitamin D insufficiency, and decreased bone mineral density. Antihypertensive drugs may increase the risk of falling. However, risk of fracture in patients treated with non-diuretic c...