Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms - Watanabe, Eizo; Hirasawa, Hiroyuki; Oda, Shigeto; Matsuda, Kenichi; Hatano, Masahiko; Tokuhisa, Takeshi (Critical care medicine, 2005)
Keywords: Adult; Aged; Aged, 80 and over; Critical Illness - mortality; Female; Gene Frequency; Genetic Carrier Screening; Hospital Mortality; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1 - blood; Interleukin-1 - genetics; Interleukin-6 - blood; Interleukin-6 - genetics; Male; Middle Aged; Multiple Organ Failure - immunology; Multiple Organ Failure - mortality; Outcome Assessment (Health Care); Polymorphism, Single Nucleotide - genetics; Prognosis; Risk Factors; Sialoglycoproteins - blood; Sialoglycoproteins - genetics; Survival Rate; Systemic Inflammatory Response Syndrome - blood; Systemic Inflammatory Response Syndrome - genetics; Tumor Necrosis Factor-alpha - genetics; Tumor Necrosis Factor-alpha - metabolism