Typical cerebral metabolic patterns in neurodegenerative brain diseases

• Published in: Movement disorders Vol. 25; no. 14; pp. 2395 - 2404
• Main Authors: Teune, Laura K., Bartels, Anna L., de Jong, Bauke M., Willemsen, Antoon T. M., Eshuis, Silvia A., de Vries, Jeroen J., van Oostrom, Joost C. H., Leenders, Klaus L.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 30.10.2010; Wiley
• Subjects: Aged; Biological and medical sciences; Brain - diagnostic imaging; Brain - metabolism; Brain - pathology; Brain Diseases - complications; Brain Diseases - diagnostic imaging; Brain Diseases - metabolism; Brain Mapping; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; dementia; differential diagnosis; FDG-PET; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Male; Medical sciences; metabolic activity; Middle Aged; Neurodegenerative Diseases - complications; Neurodegenerative Diseases - diagnostic imaging; Neurodegenerative Diseases - metabolism; Neurology; parkinsonism; Positron-Emission Tomography - methods; Retrospective Studies; FDG-PET; 2-deoxy-2-fluoroglucose; Nervous system diseases; differential diagnosis; Central nervous system; Metabolic diseases; Differential diagnostic; Encephalon; Cerebral disorder; metabolic activity; Parkinsonism; Central nervous system disease; Degenerative disease; Positron emission tomography; Dementia

The differential diagnosis of neurodegenerative brain diseases on clinical grounds is difficult, especially at an early disease stage. Several studies have found specific regional differences of brain metabolism applying [18F]‐fluoro‐deoxyglucose positron emission tomography (FDG‐PET), suggesting th...