An improved dosing schedule for ivermectin as a microfilaricidal agent against onchocerciasis

• Published in: Acta tropica Vol. 68; no. 3; pp. 269 - 275
• Main Authors: Shu, E.N, Okonkwo, P.O, Ogbodo, S.O
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.1997
• Subjects: Adolescent; Adult; Aged; Body Weight; Child; Drug Administration Schedule; Female; Filaricides - administration & dosage; Human onchocerciasis; Humans; Improved dose; Ivermectin; Ivermectin - administration & dosage; Male; Middle Aged; Onchocerciasis - drug therapy; Improved dose; Human onchocerciasis; Ivermectin
• ISSN: 0001-706X; 1873-6254
• DOI: 10.1016/S0001-706X(97)00101-0

The introduction of ivermectin therapy has proved to be the most important advance in the management and control of onchocerciaisis. By using the standard dosing schedule (150 μg/kg) in a mass chemotherapy campaign in Awhum, Nigeria, 128 (14.6%) of 875 eligible subjects used in this study were under...