Modulation of Atopy Patch Test and Skin Prick Test by Pretreatment with 1% Pimecrolimus Cream

• Published in: International Archives of Allergy and Immunology Vol. 140; no. 3; pp. 239 - 244
• Main Authors: Weissenbacher, Stephanie, Traidl-Hoffmann, Claudia, Eyerich, Kilian, Katzer, Kerstin, Braeutigam, Matthias, Loeffler, Helena, Hofmann, Heidelore, Behrendt, Heidrun, Ring, Johannes, Darsow, Ulf
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.2006; S. Karger AG
• Subjects: Adult; Allergens - adverse effects; Allergens - immunology; Allergic diseases; Animals; Biological and medical sciences; Biopsy, Needle; Cats; Cytokines - immunology; Dermatitis, Atopic - diagnosis; Dermatitis, Atopic - immunology; Dermatologic Agents - pharmacology; Dermatophagoides pteronyssinus; Double-Blind Method; Eczema; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Immunoglobulin E - blood; Immunohistochemistry; Immunopathology; Male; Medical sciences; Medical tests; Middle Aged; Original Paper; Patch Tests - methods; Pyroglyphidae - immunology; Skin allergic diseases. Stinging insect allergies; Skin diseases; Skin Tests - methods; Statistics, Nonparametric; Tacrolimus - analogs & derivatives; Tacrolimus - pharmacology; Pimecrolimus; Atopic eczema; Atopy patch test; Allergy; Immunopathology; Skin disease; Prick test; Cream; Exploration; Macrolide; Atopy; Immunology; Modulation; Eczema; Protein synthesis inhibitor; Pretreatment; Patch; Skin test

Background: In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE. Objective: It was the aim of this study to investigate the effect of pretreatment with 1% pimecrolimus cream (Elidel ® )...