Utility of cytokines to predict neonatal sepsis

• Published in: Pediatric research Vol. 81; no. 4; pp. 616 - 621
• Main Authors: Ye, Qing, Du, Li-zhong, Shao, Wen-Xia, Shang, Shi-qiang
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.04.2017; Nature Publishing Group
• Subjects: 631/45/127; 692/53/2421; 692/700/1720/3192; Area Under Curve; Biomarkers - blood; C-Reactive Protein - analysis; clinical-investigation; Cytokines; Cytokines - blood; Female; Humans; Infant, Newborn; Inflammation - blood; Interleukin-10 - blood; Interleukin-6 - blood; Male; Medicine & Public Health; Morbidity; Mortality; Neonatal Sepsis - blood; Neonatal Sepsis - diagnosis; Pediatric Surgery; Pediatrics; Prospective Studies; Regression Analysis; ROC Curve; Sensitivity and Specificity; Sepsis; Th1 Cells - cytology; Th2 Cells - cytology; Treatment Outcome

Background: Sepsis is an important cause of neonatal morbidity and mortality worldwide. Diagnosis and treatment of neonatal sepsis relies on clinical judgment and interpretation of nonspecific laboratory tests. In a prospective cohort, we measured inflammatory cytokines as a potential biomarker for...