Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 285; no. 2; pp. H669 - H678
• Main Authors: Venema, Richard C, Venema, Virginia J, Ju, Hong, Harris, M. Brennan, Snead, Connie, Jilling, Tamas, Dimitropoulou, Christiana, Maragoudakis, Michael E, Catravas, John D
• Format: Journal Article
• Language: English
• Published: United States 01.08.2003
• Subjects: Animals; Aorta - cytology; Benzoquinones; Cattle; Cells, Cultured; Endothelium, Vascular - cytology; Endothelium, Vascular - enzymology; Enzyme Inhibitors - pharmacology; Guanylate Cyclase - metabolism; HSP90 Heat-Shock Proteins - metabolism; Lactams, Macrocyclic; Muscle, Smooth, Vascular - cytology; Muscle, Smooth, Vascular - enzymology; Nitric Oxide Donors - pharmacology; Nitric Oxide Synthase - metabolism; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside - pharmacology; Quinones - pharmacology; Rats; Rats, Sprague-Dawley; Signal Transduction - drug effects; Signal Transduction - physiology

1 Vascular Biology Center, 2 Department of Pediatrics, and 3 Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912-2500; and 4 Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611-3008 Submitted 2 December 200...