Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects - Čulić, Ognjen; Eraković, Vesna; Čepelak, Ivana; Barišić, Karmela; Brajša, Karmen; Ferenčić, Željko; Galović, Ružica; Glojnarić, Ines; Manojlović, Zoran; Munić, Vesna; Novak-Mirčetić, Renata; Pavičić-Beljak, Verica; et al. (European journal of pharmacology, 2002)
Keywords: Acute-Phase Proteins - analysis; Administration, Oral; Adult; Anti-Inflammatory Agents - administration & dosage; Anti-Inflammatory Agents - blood; Anti-Inflammatory Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antioxidants - metabolism; Apoptosis; Azithromycin; Azithromycin - administration & dosage; Azithromycin - blood; Azithromycin - pharmacology; Biological and medical sciences; Bones, joints and connective tissue. Antiinflammatory agents; Cell Adhesion Molecules - blood; Chemokines - blood; Cytokine; Cytokines - blood; Degranulation; Enzyme-Linked Immunosorbent Assay; Glutathione - metabolism; Glutathione Peroxidase - metabolism; Glutathione Reductase - metabolism; Human volunteer; Humans; Male; Medical sciences; Neutrophil; Neutrophils - cytology; Neutrophils - drug effects; Neutrophils - metabolism; Nitrates - blood; Nitrites - blood; Oxidative burst; Oxidative Stress - drug effects; Pharmacology. Drug treatments; Superoxide Dismutase - metabolism; Degranulation; Neutrophil; Human volunteer; Azithromycin; Oxidative burst; Cytokine; Human; Oxidative stress; Healthy subject; Antiinflammatory agent; Oral administration; Inflammation; Oxidant; Macrolide; Antibiotic; Cell death; Inflammatory cell; Antibacterial agent; Mechanism of action; Apoptosis