Cannabis, tobacco, and caffeine use modify the blood pressure reactivity protection of ascorbic acid
Cannabis, caffeine, and tobacco use are associated with increased mesolimbic dopamine activity. Ascorbic acid (AA) modulates some dopaminergic agent effects, and was recently found to decrease systolic blood pressure (SBP) stress reactivity. To examine how AA SBP stress reactivity protection varies...
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Published in | Pharmacology, biochemistry and behavior Vol. 72; no. 4; pp. 811 - 816 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.07.2002
Elsevier Science |
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Abstract | Cannabis, caffeine, and tobacco use are associated with increased mesolimbic dopamine activity. Ascorbic acid (AA) modulates some dopaminergic agent effects, and was recently found to decrease systolic blood pressure (SBP) stress reactivity. To examine how AA SBP stress reactivity protection varies by use of these substances, data from an AA trial (Cetebe, 3000 mg/day for 14 days;
N=108) were compared by substance use level regarding SBP reactivity to the anticipation and actual experience phases of a standardized psychological stressor (10 min of public speaking and arithmetic). Self-reported never users of cannabis, persons not currently smoking tobacco, and persons consuming three or more caffeine beverages daily all exhibited AA SBP stress reactivity protection to the actual stressor, but not during the anticipation phase. Conversely, self-reported ever cannabis users, current tobacco smokers, and persons consuming less than three caffeine beverages daily exhibited the AA SBP protection during the anticipation phase, but only the lower caffeine consumption group exhibited AA protection during both phases. Covariates (neuroticism, extraversion, and depression scores, age, sex, body mass index) were all nonsignificant. Results are discussed in terms of dopaminergic effects of these substances, modulation of catecholaminergic and endothelial activity, and AA support of coping styles. |
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AbstractList | Cannabis, caffeine, and tobacco use are associated with increased mesolimbic dopamine activity. Ascorbic acid (AA) modulates some dopaminergic agent effects, and was recently found to decrease systolic blood pressure (SBP) stress reactivity. To examine how AA SBP stress reactivity protection varies by use of these substances, data from an AA trial (Cetebe, 3000 mg/day for 14 days; N=108) were compared by substance use level regarding SBP reactivity to the anticipation and actual experience phases of a standardized psychological stressor (10 min of public speaking and arithmetic). Self-reported never users of cannabis, persons not currently smoking tobacco, and persons consuming three or more caffeine beverages daily all exhibited AA SBP stress reactivity protection to the actual stressor, but not during the anticipation phase. Conversely, self-reported ever cannabis users, current tobacco smokers, and persons consuming less than three caffeine beverages daily exhibited the AA SBP protection during the anticipation phase, but only the lower caffeine consumption group exhibited AA protection during both phases. Covariates (neuroticism, extraversion, and depression scores, age, sex, body mass index) were all nonsignificant. Results are discussed in terms of dopaminergic effects of these substances, modulation of catecholaminergic and endothelial activity, and AA support of coping styles. Cannabis, caffeine, and tobacco use are associated with increased mesolimbic dopamine activity. Ascorbic acid (AA) modulates some dopaminergic agent effects, and was recently found to decrease systolic blood pressure (SBP) stress reactivity. To examine how AA SBP stress reactivity protection varies by use of these substances, data from an AA trial (Cetebe, 3000 mg/day for 14 days; N=108) were compared by substance use level regarding SBP reactivity to the anticipation and actual experience phases of a standardized psychological stressor (10 min of public speaking and arithmetic). Self-reported never users of cannabis, persons not currently smoking tobacco, and persons consuming three or more caffeine beverages daily all exhibited AA SBP stress reactivity protection to the actual stressor, but not during the anticipation phase. Conversely, self-reported ever cannabis users, current tobacco smokers, and persons consuming less than three caffeine beverages daily exhibited the AA SBP protection during the anticipation phase, but only the lower caffeine consumption group exhibited AA protection during both phases. Covariates (neuroticism, extraversion, and depression scores, age, sex, body mass index) were all nonsignificant. Results are discussed in terms of dopaminergic effects of these substances, modulation of catecholaminergic and endothelial activity, and AA support of coping styles. |
Author | Preut, Ragnar Brody, Stuart |
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Cites_doi | 10.1007/BF02253538 10.1161/01.CIR.102.12.1394 10.1016/0376-8716(82)90050-3 10.1016/S0033-3182(91)72094-X 10.1016/0006-8993(95)00494-B 10.1176/appi.ajp.157.4.632 10.1001/archinte.159.9.1007 10.1097/00005344-199911000-00010 10.1016/S0091-3057(98)00249-4 10.1016/0191-8869(95)00181-6 10.1159/000119004 10.1161/01.CIR.99.25.3234 10.1097/00006842-199803000-00014 10.1016/S0091-3057(96)00435-2 10.1016/0167-8760(95)00029-1 10.1007/s00213-001-0929-6 |
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Keywords | Cannabis Tobacco Ascorbic acid Dopamine Blood pressure Coping Stress Caffeine Human Cannabis sativa Healthy subject CNS stimulant Illicit drug Psychotropic Oral administration Cannabidaceae Cannabinoid Alkaloid Dicotyledones Angiospermae Spermatophyta Drug of abuse Xanthine derivatives Circulatory system Nicotine |
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References | Brody, Veit, Rau (BIB3) 1996; 20 Wilkinson, Megson, MacCallum, Sogo, Cockcroft, Webb (BIB20) 1999; 34 Gilbert (BIB8) 1995 Garrett, Griffiths (BIB7) 1997; 57 Gokce, Keaney, Frei, Holbrook, Olesiak, Zachariah, Leeuwenburgh, Heinecke, Vita (BIB9) 1999; 99 Bond, Mills, Caprarola, Vaccaro, Adams, Blakely, Roltsch, Hatfield, Davis, Franks, Fairfax, Banks (BIB2) 1999; 9 Brody, Preut, Schommer, Schürmeyer (BIB5) 2002; 159 Markovitz, Raczynski, Wallace, Chettur, Chesney (BIB15) 1998; 60 Salokangas, Vilkman, Ilonen, Taiminen, Bergman, Haaparanta, Solin, Alanen, Syvalahti, Hietala (BIB19) 2000; 157 Kamarck, Eranen, Jennings, Manuck, Everson, Kaplan, Salonen (BIB12) 2000; 102 Eysenck (BIB6) 1974 Kirschbaum, Pirke, Hellhammer (BIB13) 1993; 28 al'Absi, Everson, Lovallo (BIB1) 1995; 20 Gulley, Rebec (BIB10) 1999; 63 Markianos, Stefanis (BIB14) 1982; 9 Pauli, Rau, Zhuang, Brody, Birbaumer (BIB17) 1993; 111 Pierce, Rowlett, Rebec, Bardo (BIB18) 1995; 688 Mills, Dimsdale (BIB16) 1991; 32 Hautzinger, Bailer, Worall, Keller (BIB11) 1994 Brody, Veit, Rau (BIB4) 1999; 159 Pierce (10.1016/S0091-3057(02)00751-7_BIB18) 1995; 688 Gilbert (10.1016/S0091-3057(02)00751-7_BIB8) 1995 Markianos (10.1016/S0091-3057(02)00751-7_BIB14) 1982; 9 Pauli (10.1016/S0091-3057(02)00751-7_BIB17) 1993; 111 Salokangas (10.1016/S0091-3057(02)00751-7_BIB19) 2000; 157 Wilkinson (10.1016/S0091-3057(02)00751-7_BIB20) 1999; 34 Hautzinger (10.1016/S0091-3057(02)00751-7_BIB11) 1994 Gulley (10.1016/S0091-3057(02)00751-7_BIB10) 1999; 63 Brody (10.1016/S0091-3057(02)00751-7_BIB5) 2002; 159 Kamarck (10.1016/S0091-3057(02)00751-7_BIB12) 2000; 102 Markovitz (10.1016/S0091-3057(02)00751-7_BIB15) 1998; 60 Kirschbaum (10.1016/S0091-3057(02)00751-7_BIB13) 1993; 28 Mills (10.1016/S0091-3057(02)00751-7_BIB16) 1991; 32 Brody (10.1016/S0091-3057(02)00751-7_BIB4) 1999; 159 Garrett (10.1016/S0091-3057(02)00751-7_BIB7) 1997; 57 Gokce (10.1016/S0091-3057(02)00751-7_BIB9) 1999; 99 Eysenck (10.1016/S0091-3057(02)00751-7_BIB6) 1974 al'Absi (10.1016/S0091-3057(02)00751-7_BIB1) 1995; 20 Bond (10.1016/S0091-3057(02)00751-7_BIB2) 1999; 9 Brody (10.1016/S0091-3057(02)00751-7_BIB3) 1996; 20 |
References_xml | – volume: 60 start-page: 186 year: 1998 end-page: 191 ident: BIB15 article-title: Cardiovascular reactivity to video game predicts subsequent blood pressure increases in young men: the Cardia study publication-title: Psychosom Med contributor: fullname: Chesney – volume: 20 start-page: 155 year: 1995 end-page: 160 ident: BIB1 article-title: Hypertension risk factors and cardiovascular reactivity to mental stress in young men publication-title: Int J Psychophysiol contributor: fullname: Lovallo – volume: 57 start-page: 533 year: 1997 end-page: 541 ident: BIB7 article-title: The role of dopamine in the behavioral effects of caffeine in animals and humans publication-title: Pharmacol, Biochem Behav contributor: fullname: Griffiths – volume: 159 start-page: 319 year: 2002 end-page: 324 ident: BIB5 article-title: A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress publication-title: Psychopharmacology contributor: fullname: Schürmeyer – volume: 157 start-page: 632 year: 2000 end-page: 634 ident: BIB19 article-title: High levels of dopamine activity in the basal ganglia of cigarette smokers publication-title: Am J Psychiatry contributor: fullname: Hietala – volume: 20 start-page: 375 year: 1996 end-page: 380 ident: BIB3 article-title: Neuroticism but not cardiovascular stress reactivity is associated with less longitudinal blood pressure increase publication-title: Pers Individ Differ contributor: fullname: Rau – volume: 9 start-page: 104 year: 1999 end-page: 110 ident: BIB2 article-title: Aerobic exercise attenuates blood pressure reactivity to cold pressor test in normotensive, young adult African-American women publication-title: Ethn Dis contributor: fullname: Banks – year: 1995 ident: BIB8 article-title: Smoking: individual difference, psychopathology, and emotion contributor: fullname: Gilbert – volume: 28 start-page: 76 year: 1993 end-page: 81 ident: BIB13 article-title: The ‘Trier Social Stress Test’—a tool for investigating psychobiological stress responses in a laboratory setting publication-title: Neuropsychobiology contributor: fullname: Hellhammer – year: 1974 ident: BIB6 article-title: Eysenck Persönlichkeits Inventar contributor: fullname: Eysenck – volume: 63 start-page: 125 year: 1999 end-page: 129 ident: BIB10 article-title: Modulatory effects of ascorbate, alone or with haloperidol, on a lever-release conditioned avoidance response task publication-title: Pharmacol, Biochem Behav contributor: fullname: Rebec – volume: 102 start-page: 1394 year: 2000 end-page: 1399 ident: BIB12 article-title: Anticipatory blood pressure responses to exercise are associated with left ventricular mass in Finnish men: Kuopio Ischemic Heart Disease Risk Factor Study publication-title: Circulation contributor: fullname: Salonen – volume: 32 start-page: 209 year: 1991 end-page: 220 ident: BIB16 article-title: Cardiovascular reactivity to psychosocial stressors. A review of the effects of beta-blockade publication-title: Psychosomatics contributor: fullname: Dimsdale – volume: 99 start-page: 3234 year: 1999 end-page: 3240 ident: BIB9 article-title: Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease publication-title: Circulation contributor: fullname: Vita – volume: 688 start-page: 21 year: 1995 end-page: 26 ident: BIB18 article-title: Ascorbate potentiates amphetamine-induced conditioned place preference and forebrain dopamine release in rats publication-title: Brain Res contributor: fullname: Bardo – year: 1994 ident: BIB11 article-title: Beck-Depressions-Inventar (BDI) contributor: fullname: Keller – volume: 9 start-page: 251 year: 1982 end-page: 255 ident: BIB14 article-title: Effects of acute cannabis use and short-term deprivation on plasma prolactin and dopamine-beta-hydroxylase in long-term users publication-title: Drug Alcohol Depend contributor: fullname: Stefanis – volume: 111 start-page: 472 year: 1993 end-page: 476 ident: BIB17 article-title: Effects of smoking on thermal pain threshold in deprived and minimally deprived smokers publication-title: Psychopharmacology contributor: fullname: Birbaumer – volume: 34 start-page: 690 year: 1999 end-page: 693 ident: BIB20 article-title: Oral vitamin C reduces arterial stiffness and platelet aggregation in humans publication-title: J Cardiovasc Pharmacol contributor: fullname: Webb – volume: 159 start-page: 1007 year: 1999 end-page: 1008 ident: BIB4 article-title: Four-year test–retest reliability of self-measured blood pressure publication-title: Arch Intern Med contributor: fullname: Rau – volume: 9 start-page: 104 year: 1999 ident: 10.1016/S0091-3057(02)00751-7_BIB2 article-title: Aerobic exercise attenuates blood pressure reactivity to cold pressor test in normotensive, young adult African-American women publication-title: Ethn Dis contributor: fullname: Bond – volume: 111 start-page: 472 year: 1993 ident: 10.1016/S0091-3057(02)00751-7_BIB17 article-title: Effects of smoking on thermal pain threshold in deprived and minimally deprived smokers publication-title: Psychopharmacology doi: 10.1007/BF02253538 contributor: fullname: Pauli – volume: 102 start-page: 1394 year: 2000 ident: 10.1016/S0091-3057(02)00751-7_BIB12 article-title: Anticipatory blood pressure responses to exercise are associated with left ventricular mass in Finnish men: Kuopio Ischemic Heart Disease Risk Factor Study publication-title: Circulation doi: 10.1161/01.CIR.102.12.1394 contributor: fullname: Kamarck – volume: 9 start-page: 251 year: 1982 ident: 10.1016/S0091-3057(02)00751-7_BIB14 article-title: Effects of acute cannabis use and short-term deprivation on plasma prolactin and dopamine-beta-hydroxylase in long-term users publication-title: Drug Alcohol Depend doi: 10.1016/0376-8716(82)90050-3 contributor: fullname: Markianos – year: 1994 ident: 10.1016/S0091-3057(02)00751-7_BIB11 contributor: fullname: Hautzinger – volume: 32 start-page: 209 year: 1991 ident: 10.1016/S0091-3057(02)00751-7_BIB16 article-title: Cardiovascular reactivity to psychosocial stressors. A review of the effects of beta-blockade publication-title: Psychosomatics doi: 10.1016/S0033-3182(91)72094-X contributor: fullname: Mills – volume: 688 start-page: 21 year: 1995 ident: 10.1016/S0091-3057(02)00751-7_BIB18 article-title: Ascorbate potentiates amphetamine-induced conditioned place preference and forebrain dopamine release in rats publication-title: Brain Res doi: 10.1016/0006-8993(95)00494-B contributor: fullname: Pierce – volume: 157 start-page: 632 year: 2000 ident: 10.1016/S0091-3057(02)00751-7_BIB19 article-title: High levels of dopamine activity in the basal ganglia of cigarette smokers publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.157.4.632 contributor: fullname: Salokangas – volume: 159 start-page: 1007 year: 1999 ident: 10.1016/S0091-3057(02)00751-7_BIB4 article-title: Four-year test–retest reliability of self-measured blood pressure publication-title: Arch Intern Med doi: 10.1001/archinte.159.9.1007 contributor: fullname: Brody – volume: 34 start-page: 690 year: 1999 ident: 10.1016/S0091-3057(02)00751-7_BIB20 article-title: Oral vitamin C reduces arterial stiffness and platelet aggregation in humans publication-title: J Cardiovasc Pharmacol doi: 10.1097/00005344-199911000-00010 contributor: fullname: Wilkinson – volume: 63 start-page: 125 year: 1999 ident: 10.1016/S0091-3057(02)00751-7_BIB10 article-title: Modulatory effects of ascorbate, alone or with haloperidol, on a lever-release conditioned avoidance response task publication-title: Pharmacol, Biochem Behav doi: 10.1016/S0091-3057(98)00249-4 contributor: fullname: Gulley – volume: 20 start-page: 375 year: 1996 ident: 10.1016/S0091-3057(02)00751-7_BIB3 article-title: Neuroticism but not cardiovascular stress reactivity is associated with less longitudinal blood pressure increase publication-title: Pers Individ Differ doi: 10.1016/0191-8869(95)00181-6 contributor: fullname: Brody – volume: 28 start-page: 76 year: 1993 ident: 10.1016/S0091-3057(02)00751-7_BIB13 article-title: The ‘Trier Social Stress Test’—a tool for investigating psychobiological stress responses in a laboratory setting publication-title: Neuropsychobiology doi: 10.1159/000119004 contributor: fullname: Kirschbaum – year: 1974 ident: 10.1016/S0091-3057(02)00751-7_BIB6 contributor: fullname: Eysenck – volume: 99 start-page: 3234 year: 1999 ident: 10.1016/S0091-3057(02)00751-7_BIB9 article-title: Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease publication-title: Circulation doi: 10.1161/01.CIR.99.25.3234 contributor: fullname: Gokce – volume: 60 start-page: 186 year: 1998 ident: 10.1016/S0091-3057(02)00751-7_BIB15 article-title: Cardiovascular reactivity to video game predicts subsequent blood pressure increases in young men: the Cardia study publication-title: Psychosom Med doi: 10.1097/00006842-199803000-00014 contributor: fullname: Markovitz – year: 1995 ident: 10.1016/S0091-3057(02)00751-7_BIB8 contributor: fullname: Gilbert – volume: 57 start-page: 533 year: 1997 ident: 10.1016/S0091-3057(02)00751-7_BIB7 article-title: The role of dopamine in the behavioral effects of caffeine in animals and humans publication-title: Pharmacol, Biochem Behav doi: 10.1016/S0091-3057(96)00435-2 contributor: fullname: Garrett – volume: 20 start-page: 155 year: 1995 ident: 10.1016/S0091-3057(02)00751-7_BIB1 article-title: Hypertension risk factors and cardiovascular reactivity to mental stress in young men publication-title: Int J Psychophysiol doi: 10.1016/0167-8760(95)00029-1 contributor: fullname: al'Absi – volume: 159 start-page: 319 year: 2002 ident: 10.1016/S0091-3057(02)00751-7_BIB5 article-title: A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress publication-title: Psychopharmacology doi: 10.1007/s00213-001-0929-6 contributor: fullname: Brody |
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SubjectTerms | Adaptation, Psychological - drug effects Adult Antioxidants - pharmacology Ascorbic acid Ascorbic Acid - antagonists & inhibitors Ascorbic Acid - pharmacology Biological and medical sciences Blood pressure Blood Pressure - drug effects Caffeine Caffeine - pharmacology Cannabis Central Nervous System Stimulants - pharmacology Coping Dopamine Female General and cellular metabolism. Vitamins Humans Male Marijuana Smoking - physiopathology Medical sciences Pharmacology. Drug treatments Regression Analysis Smoking - physiopathology Stress Stress, Psychological - physiopathology Surveys and Questionnaires Tobacco |
Title | Cannabis, tobacco, and caffeine use modify the blood pressure reactivity protection of ascorbic acid |
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