Exosomes from MSCs overexpressing microRNA-223-3p attenuate cerebral ischemia through inhibiting microglial M1 polarization mediated inflammation - Zhao, Yangmin; Gan, Yunxiao; Xu, Gewei; Hua, Kouzhen; Liu, Dandan (Life sciences (1973), 2020)
Keywords: Cerebral blood flow; Cerebral infarction; Cerebral ischemia; cortex; Cysteinyl leukotriene receptor 2 (CysLT2R); Cytokines; Deprivation; Exosomes; Flow cytometry; Gene expression; glucose; hippocampus; In vivo methods and tests; infarction; Inflammation; Inflammatory response; Ischemia; Leukotrienes; Mesenchymal stem cell-derived exosomes (MSC-exos); Microglia; Microglial M1 polarization; MicroRNA-223; miRNA; neuroglia; Neurological diseases; Occlusion; oxygen; Polarization; protein synthesis; Proteins; Reperfusion; reperfusion injury; Ribonucleic acid; RNA; secretion; Surgery; therapeutics; Western blotting; Cerebral ischemia; Mesenchymal stem cell-derived exosomes (MSC-exos); Microglial M1 polarization; Cysteinyl leukotriene receptor 2 (CysLT2R); MicroRNA-223