Serum semicarbazide-sensitive amine oxidase (SSAO) activity is an independent marker of carotid atherosclerosis

• Published in: Clinica chimica acta Vol. 323; no. 1; pp. 139 - 146
• Main Authors: Karádi, István, Mészáros, Zsuzsa, Csányi, Attila, Szombathy, Tamás, Hosszúfalusi, Nóra, Romics, László, Magyar, Kálmán
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier B.V 01.09.2002; Elsevier
• Subjects: Adult; Aged; Amine Oxidase (Copper-Containing) - blood; Arteriosclerosis - blood; Arteriosclerosis - complications; Arteriosclerosis - enzymology; Associated diseases and complications; Biological and medical sciences; Biomarkers - blood; Cardiovascular system; Carotid Artery Diseases - blood; Carotid Artery Diseases - complications; Carotid Artery Diseases - enzymology; Carotid atherosclerosis; Carotid sonography; Diabetes mellitus; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - enzymology; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Macrovascular complications; Male; Medical sciences; Middle Aged; Oxidative stress; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Risk Factors; SSAO; Oxidative stress; HDL; IMT; Macrovascular complications; VAP-1; Carotid atherosclerosis; Carotid sonography; LDL; Diabetes mellitus; SSAO; NIDDM; BMI; Endocrinopathy; Human; Biochemical analysis; Enzyme; Coronary artery; Oxidase; Biological marker; Semicarbazides; Cardiovascular disease; Coronary heart disease; Vascular disease; Atherosclerosis; Complication; Serum; Oxidoreductases; Amine oxide; Diagnosis; Technique

Background: Clinical and experimental studies suggest that increased activity of semicarbazide-sensitive amine oxidase (SSAO) and the production of cytotoxic metabolites (e.g., formaldehyde and hydrogen peroxide) may play an important role in the pathogenesis of atherosclerosis. The present study wa...