5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix

• Published in: Journal of natural medicines Vol. 62; no. 2; pp. 164 - 167
• Main Authors: Lin, An-Shen, Qian, Keduo, Usami, Yoshihide, Lin, Li, Itokawa, Hideji, Hsu, Charleson, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
• Format: Journal Article
• Language: English
• Published: Japan Springer Japan 01.04.2008
• Subjects: Anemia, Sickle Cell - drug therapy; Biomedical and Life Sciences; Biomedicine; Chromatography, High Pressure Liquid; Complementary & Alternative Medicine; Disaccharides - analysis; Drugs, Chinese Herbal - chemistry; Furaldehyde - analogs & derivatives; Furaldehyde - analysis; Furaldehyde - therapeutic use; Furans - analysis; Glucosides - analysis; Hot Temperature; Humans; Medicinal Chemistry; Original Paper; Pharmacology/Toxicology; Pharmacy; Plant Roots - chemistry; Plant Sciences; Rehmannia - chemistry; Reversed-phase HPLC; 5-Hydroxymethylfurfural (5-HMF); Rehmanniae Radix; Traditional Chinese medicine (TCM)

Rehmanniae Radix (Di Huang) is one of the most important traditional Chinese medicines (TCM), and is used for multiple therapeutic purposes. In our investigation of the chemical constituents of Rehmanniae Radix, steamed roots were prepared by the classical processing method. Reversed-phase HPLC of t...