The loss of susceptibility to apoptosis in exudated tissue neutrophils is associated with their nuclear factor-κB activation - Hotta, Koichi; Niwa, Masayuki; Hara, Akira; Ohno, Takatoshi; Wang, Xiaodan; Matsuno, Hiroyuki; Kozawa, Osamu; Ito, Hidenori; Kato, Kanefusa; Otsuka, Takanobu; Matsui, Nobuo; Uematsu, Toshihiko (European journal of pharmacology, 2001)
Keywords: Analysis of the immune response. Humoral and cellular immunity; Apoptosis; Apoptosis - drug effects; Biological and medical sciences; Caspase 3; Caspases - metabolism; circulating blood; Cyclophosphamide - pharmacology; DNA Fragmentation; Enzyme Activation; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Immunobiology; Inflammation; Miscellaneous; Molecular and cellular biology; Neutrophil; Neutrophils - drug effects; Neutrophils - physiology; NF-kappa B - physiology; Regulatory factors and their cellular receptors; Superoxides - metabolism; tissue; Transcription factor; Tumor Necrosis Factor-alpha - pharmacology; Transcription factor; Neutrophil; Apoptosis; Human; Immunopathology; Biological fluid; Healthy subject; Diseases of the osteoarticular system; Tissue specificity; Autoimmune disease; Inflammatory joint disease; Cellular immunity; Inflammation; In vitro; Biological activity; Blood; Synovial fluid; Chronic; Cell death; Rheumatoid arthritis; Defense mechanism; Transcription factor NFκB; Mechanism of action; Saliva; Tumor necrosis factor α