Management of Pregnancy in a Patient with Severe Hemophilia Type A

Abstract Hemophilia type A is a rare inherited bleeding disorder with a diversity of clinical manifestations ranging from persistent bleeding after minor trauma, spontaneous deep muscle or joint hemorrhage, to intracranial hemorrhage. As an X-linked disorder, hemophilia is rare in females and theref...

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Bibliographic Details
Published inAmerican journal of perinatology reports Vol. 3; no. 1; pp. 029 - 032
Main Authors Sharma, Vipra, Khalid, Aysha, Cohen, Alice J.
Format Journal Article
LanguageEnglish
Published 333 Seventh Avenue, New York, NY 10001, USA Thieme Medical Publishers 01.05.2013
Thieme Medical Publishers, Inc
Subjects
bolus factor therapy
hemophilia a
obstetric management
pregnancy
hemophilia A
obstetric management
pregnancy
bolus factor therapy
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Summary:Abstract Hemophilia type A is a rare inherited bleeding disorder with a diversity of clinical manifestations ranging from persistent bleeding after minor trauma, spontaneous deep muscle or joint hemorrhage, to intracranial hemorrhage. As an X-linked disorder, hemophilia is rare in females and therefore there is little experience with pregnancy and no standardized guidelines to prevent bleeding antepartum, at delivery, and postpartum. We report the clinical course and management of a woman with severe hemophilia A who on two occasions had uncomplicated pregnancies and vaginal deliveries at term utilizing bolus recombinant factor VIII concentrate.
ISSN:2157-6998
2157-7005
DOI:10.1055/s-0032-1331376