Development of severe bronchopulmonary dysplasia is associated with alterations in fecal volatile organic compounds

• Published in: Pediatric research Vol. 83; no. 2; pp. 412 - 419
• Main Authors: Berkhout, Daniel J C, Niemarkt, Hendrik J, Benninga, Marc A, Budding, Andries E, van Kaam, Anton H, Kramer, Boris W, Pantophlet, Charlene M, van Weissenbruch, Mirjam M, de Boer, Nanne K H, de Meij, Tim G J
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.02.2018; Nature Publishing Group
• Subjects: 692/4020/2741/2135; 692/699/1785; 692/700/1720/3187; 692/700/1750; Biomarkers; Feces; Lung diseases; Medicine; Medicine & Public Health; Microbiota; Pediatric Surgery; Pediatrics; population-study; VOCs; Volatile organic compounds

Background The aim of this study was to evaluate the potential of fecal volatile organic compounds (VOCs), obtained by means of an electronic nose device (Cyranose 320), as early non-invasive biomarker for BPD. Methods In this nested case–control study performed at three Neonatal Intensive Care Unit...