Flexible parylene-thread bioprobe and the sewing method for in vivo neuronal recordings

• Published in: Sensors and actuators. B, Chemical Vol. 316; p. 127835
• Main Authors: Yamashita, Koji, Sawahata, Hirohito, Yamagiwa, Shota, Morikawa, Yusuke, Numano, Rika, Koida, Kowa, Kawano, Takeshi
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.08.2020; Elsevier Science Ltd
• Subjects: Brain; Electrophysiology; Flexible device; Implantation; In vivo methods and tests; Microelectrode; Microelectrodes; Muscle; Needles; Neural recording; Penetration; Recording; Sewing; Surgical implants; Tissues; Microelectrode; Brain; Flexible device; Neural recording; Muscle

•We fabricated a flexible parylene-thread bioprobe and proposed the implantation method based on conventional sewing method.•A device-holding protocol was proposed to enable a stress-free “catch” and “release” of the needle.•EMG signals were recorded from the mouse’s MG muscle.•Both the LFP and the...