α-Selective glycosylation with 5-thioglucopyranosyl donors; synthesis of an IsoMaltotetraoside mimic composed of 5-thioglucopyranose units
A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. This methodology was utilized in the synthesis of an isomaltotetraoside analogue. A general method for α-selective glycosylation with 5-thiogluc...
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Published in | Bioorganic & medicinal chemistry letters Vol. 13; no. 6; pp. 1063 - 1066 |
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Main Authors | , , , , , |
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24.03.2003
Elsevier |
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Abstract | A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. This methodology was utilized in the synthesis of an isomaltotetraoside analogue.
A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. A isomaltotetraoside analogue was synthesized as the application. |
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AbstractList | A general method for alpha-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. This methodology was utilized in the synthesis of an isomaltotetraoside analogue. A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. This methodology was utilized in the synthesis of an isomaltotetraoside analogue. A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. A isomaltotetraoside analogue was synthesized as the application. |
Author | Hashimoto, Masaru Matsuda, Hiroko Ohara, Keiichiro Miyairi, Kazuo Okuno, Toshikatsu Morii, Yasuharu |
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Cites_doi | 10.1139/v93-239 10.2174/0929867306666220207213740 10.1016/S0040-4039(00)74054-8 10.1002/anie.198602121 10.1021/jo011142u 10.1021/bi025541a 10.1042/bj3210557 10.1016/S0957-4166(00)80386-9 10.1016/S0040-4039(02)01760-4 10.1021/jo9800356 10.1016/S0040-4039(00)86974-9 |
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Snippet | A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed.... A general method for alpha-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed.... |
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SubjectTerms | Carbohydrate Sequence Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Exact sciences and technology Glucose - analogs & derivatives Glucose - chemistry Glycosylation Indicators and Reagents Models, Molecular Molecular Mimicry Molecular Sequence Data Monosaccharides - chemistry Oligosaccharides - chemistry Organic chemistry Preparations and properties |
Title | α-Selective glycosylation with 5-thioglucopyranosyl donors; synthesis of an IsoMaltotetraoside mimic composed of 5-thioglucopyranose units |
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