Rapid recovery of sensory function in blind cave fish treated with anemone repair proteins

• Published in: Hearing research Vol. 174; no. 1; pp. 296 - 304
• Main Authors: Berg, Astrid, Watson, Glen M
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.12.2002; Elsevier
• Subjects: Adenosine Triphosphate - pharmacology; Animals; Biological and medical sciences; Blindness - physiopathology; Calcium - analysis; Cellular Senescence - physiology; Drug Synergism; Fishes - physiology; Fundamental and applied biological sciences. Psychology; Hair cell; Hair Cells, Auditory - drug effects; Hair Cells, Auditory - physiopathology; Neuromast; Orientation - drug effects; Proteins - pharmacology; Receptors, Purinergic P2 - metabolism; Receptors, Purinergic P2X4; Recovery of Function; Rheology; Rheotaxis; Sea Anemones - metabolism; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors; Tip link; Vertebrates: nervous system and sense organs; Water - chemistry; Rheotaxis; Neuromast; Hair cell; Tip link; Calcium; Ciliated cell; Haliplanella luciae; Acousticolateralis system; Recovery; Protein; Coelenterata; Vertebrata; Lateral line; Purinergic receptor; Pisces; Cnidaria; Invertebrata; ATP

Blind cave fish employ superficial neuromasts to detect currents [Baker, C.F. and J.C. Montgomery, J. Comp. Physiol. A 184 (1999) 519–527]. Briefly exposing fish to calcium-free water significantly reduces the ability of the fish to perform rheotaxis (i.e., to orient properly in currents). Spontaneo...