Predicting drug–disease associations through layer attention graph convolutional network

• Published in: Briefings in bioinformatics Vol. 22; no. 4
• Main Authors: Yu, Zhouxin, Huang, Feng, Zhao, Xiaohan, Xiao, Wenjie, Zhang, Wen
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.07.2021; Oxford Publishing Limited (England)
• Subjects: Artificial neural networks; Computer applications; Convolution; Disease; Drug development; Predictions; Similarity; graph convolutional network; disease; drug–disease association prediction; layer attention; drug

Abstract Background: Determining drug–disease associations is an integral part in the process of drug development. However, the identification of drug–disease associations through wet experiments is costly and inefficient. Hence, the development of efficient and high-accuracy computational methods f...