LDBlockShow: a fast and convenient tool for visualizing linkage disequilibrium and haplotype blocks based on variant call format files

• Published in: Briefings in bioinformatics Vol. 22; no. 4
• Main Authors: Dong, Shan-Shan, He, Wei-Ming, Ji, Jing-Jing, Zhang, Chi, Guo, Yan, Yang, Tie-Lin
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.07.2021; Oxford Publishing Limited (England)
• Subjects: Annotations; Format; Haplotypes; Linkage disequilibrium; Population genetics; Population studies; Single-nucleotide polymorphism; Subgroups; visualization; VCF files; haplotype block; linkage disequilibrium

Abstract The triangular correlation heatmap aiming to visualize the linkage disequilibrium (LD) pattern and haplotype block structure of SNPs is ubiquitous component of population-based genetic studies. However, current tools suffered from the problem of time and memory consuming. Here, we developed...