Nosocomial transmission of tuberculosis to a nurse demonstrated by means of spoligotyping of a formalin-fixed bronchial biopsy

• Published in: Netherlands journal of medicine Vol. 59; no. 3; pp. 152 - 157
• Main Authors: van der Zanden, A.G.M., Bosje, T., Heilmann, F.G.C., van Soolingen, D.
• Format: Journal Article
• Language: English
• Published: Alphen aan den Rijn Elsevier B.V 01.09.2001; Van zuiden
• Subjects: Bacterial diseases; Biological and medical sciences; Biopsy - methods; Bronchitis - diagnosis; Bronchitis - drug therapy; Bronchitis - microbiology; Cross Infection - diagnosis; Cross Infection - drug therapy; Cross Infection - microbiology; Cross Infection - transmission; Diagnosis, Differential; DNA Fingerprinting; DNA, Bacterial - analysis; DNA, Bacterial - genetics; Female; Human bacterial diseases; Humans; Infectious Disease Transmission, Patient-to-Professional - methods; Infectious diseases; Medical sciences; Mycobacterium tuberculosis; Mycobacterium tuberculosis - genetics; Nurses; PCR; Polymorphism, Genetic; RFLP; Serotyping - methods; Students, Nursing; Tomography, X-Ray Computed; Tropical medicine; Tuberculosis and atypical mycobacterial infections; Tuberculosis, Pulmonary - diagnosis; Tuberculosis, Pulmonary - drug therapy; Tuberculosis, Pulmonary - microbiology; Tuberculosis, Pulmonary - transmission; Mycobacterium tuberculosis; ZN; Nurses; PCR; RFLP; Human; Surgical biopsy; Nosocomial infection; Radiodiagnosis; Respiratory disease; Transmission; Bronchus; Spoligotyping; Mycobacterial infection; Infection; Case study; Polymerase chain reaction; Tuberculosis; Surgery; Young adult; Bacteriosis; Bronchus disease; Medical imagery; Female; Computerized axial tomography; Diagnosis; Molecular biology; Nurse

Background: Tuberculosis was diagnosed in a student nurse. The source of infection was unknown and no positive culture was available. Methods: The diagnosis of tuberculous bronchitis was established on the grounds of a positive Mantoux test, the pathology of a bronchial biopsy and the results of a C...