Associations of oral fluid MMP‐8 with periodontitis in Swiss adult subjects

• Published in: Oral diseases Vol. 24; no. 3; pp. 449 - 455
• Main Authors: Mauramo, M, Ramseier, AM, Mauramo, E, Buser, A, Tervahartiala, T, Sorsa, T, Waltimo, T
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.04.2018
• Subjects: Adult; Area Under Curve; Biomarkers - metabolism; Bleeding; Body mass index; Bone marrow; Bone marrow transplantation; Collagen; Collagenase; Cross-Sectional Studies; Diagnosis; Female; gingival crevicular fluid; Gingival Crevicular Fluid - metabolism; Gum disease; Humans; Male; Matrix Metalloproteinase 8 - metabolism; Middle Aged; MMP‐8; normal population; oral fluid; Periodontal Index; Periodontitis; Periodontitis - diagnosis; Periodontitis - metabolism; ROC Curve; Saliva; Saliva - metabolism; Smoking; Statistical analysis; Switzerland; Teeth; Young Adult; saliva; gingival crevicular fluid; MMP-8; normal population; oral fluid; periodontitis

Objective MMP‐8 is a prominent collagenase in periodontal disease. This cross‐sectional study examined whether MMP‐8 levels in saliva and gingival crevicular fluid (GCF) are associated with periodontitis in a Swiss population. Subjects and Methods A total of 258 subjects (107 m, 151 f, mean age: 43....