Early childhood exposure to short periods of sevoflurane is not associated with later, lasting cognitive deficits

• Published in: Pediatric anesthesia Vol. 26; no. 10; pp. 1018 - 1025
• Main Authors: Poor Zamany Nejat Kermany, Mahtab, Roodneshin, Fatemeh, Ahmadi Dizgah, Niloofar, Gerami, Ebrahim, Riahi, Esmail
• Format: Journal Article
• Language: English
• Published: France Blackwell Publishing Ltd 01.10.2016; Wiley Subscription Services, Inc
• Subjects: Adolescent; Anesthesia; Anesthetics, Inhalation - adverse effects; Brain - drug effects; Child; Child, Preschool; children; Cognition Disorders - chemically induced; cognitive performance; Cohort Studies; digit span; Female; Humans; Male; Methyl Ethers - adverse effects; Retrospective Studies; sevoflurane; verbal fluency; digit span; sevoflurane; cognitive performance; verbal fluency; children; anesthesia

Summary Background A detrimental effect of commonly used anesthetics on the neurodevelopmental and behavioral parameters has long been shown in young animals subjected to early childhood anesthesia. Epidemiologic studies suggest the possibility of a modestly elevated risk of adverse neurodevelopment...