Sleep disturbance by pramipexole is modified by Meis1 in mice

• Published in: Journal of sleep research Vol. 27; no. 4; pp. e12557 - n/a
• Main Authors: Salminen, Aaro V., Schormair, Barbara, Flachskamm, Cornelia, Torres, Miguel, Müller‐Myhsok, Bertram, Kimura, Mayumi, Winkelmann, Juliane
• Format: Journal Article
• Language: English
• Published: England 01.08.2018
• Subjects: animal model; dopamine agonist; restless legs syndrome; sleep architecture; sleep architecture; dopamine agonist; animal model; restless legs syndrome

Summary Meis homeobox 1 (Meis1) is a transcription factor functioning in the development of the nervous system and the cardiovascular system. Both common and rare variants within the gene have been associated with restless legs syndrome (RLS), while its association with symptoms of insomnia has also...