Melatonin improves the fertilization capacity and developmental ability of bovine oocytes by regulating cytoplasmic maturation events

• Published in: Journal of pineal research Vol. 64; no. 1
• Main Authors: Zhao, Xue‐Ming, Wang, Na, Hao, Hai‐Sheng, Li, Chong‐Yang, Zhao, Ya‐Han, Yan, Chang‐Liang, Wang, Hao‐Yu, Du, Wei‐Hua, Wang, Dong, Liu, Yan, Pang, Yun‐Wei, Zhu, Hua‐Bin
• Format: Journal Article
• Language: English
• Published: England 01.01.2018
• Subjects: Animals; bovine; Cattle; Cells, Cultured; Cytoplasm - drug effects; Cytoplasm - metabolism; cytoplasmic maturation; Glutathione - metabolism; in vitro maturation; melatonin; Melatonin - pharmacology; oocytes; Oocytes - drug effects; Oocytes - metabolism; Reactive Oxygen Species - metabolism; bovine; in vitro maturation; cytoplasmic maturation; melatonin; oocytes

Melatonin is a well‐characterized antioxidant that has been successfully used to protect oocytes from reactive oxygen species during in vitro maturation (IVM), resulting in improved fertilization capacity and development ability. However, the mechanism via which melatonin improves oocyte fertilizati...