Autoantibodies to type I interferons in patients with systemic mastocytosis

• Published in: The journal of allergy and clinical immunology. Global Vol. 3; no. 3; p. 100273
• Main Authors: Cao, Vivian, Lee, Serena J., Bai, Yun, Holland, Steven M., Rosen, Lindsey B., Metcalfe, Dean D., Komarow, Hirsh D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2024; Elsevier
• Subjects: Autoantibodies; autoimmune; Brief Report; COVID-19; cytokines; inflammatory; mast cell; mastocytosis; type I interferons; COVID-19; Autoantibodies; FI; autoimmune; mastocytosis; inflammatory; mast cell; cytokines; MCA; SM; type I interferons

Autoantibodies to type I interferons have been identified in association with a variety of inflammatory and autoimmune diseases. Type I interferons have demonstrated inhibitory effects on mast cell proliferation and degranulation. Systemic mastocytosis (SM) is a disease characterized by increased ma...