Melatonin prevents experimental central serous chorioretinopathy in rats

• Published in: Journal of pineal research Vol. 73; no. 1; pp. e12802 - n/a
• Main Authors: Yu, Shanshan, Cui, Kaixuan, Wu, Peiqi, Wu, Benjuan, Lu, Xi, Huang, Rong, Tang, Xiaoyu, Lin, Jianqiang, Yang, Boyu, Zhao, Jinfeng, He, Qingjing, Liang, Xiaoling, Xu, Yue
• Format: Journal Article
• Language: English
• Published: England 01.08.2022
• Subjects: aldosterone; blood–retinal barrier; central serous chorioretinopathy; choroidal vasculature; IL‐17A/NF‐κB signaling pathway; inflammation; melatonin; blood-retinal barrier; choroidal vasculature; inflammation; aldosterone; IL-17A/NF-κB signaling pathway; melatonin; central serous chorioretinopathy

Central serous chorioretinopathy (CSC) is a vision‐threatening disease with no validated treatment and unclear pathogenesis. It is characterized by dilation and leakage of choroidal vasculature, resulting in the accumulation of subretinal fluid, and serous detachment of the neurosensory retina. Nume...