Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C - Chen, Li; Chen, Yan-ming; Wang, Li-jun; Wei, Jun; Tan, Yao-zong; Zhou, Jing-ya; Yang, Yang; Chen, Yu-ming; Ling, Wen-hua; Zhu, Hui-lian (Diabetes/metabolism research and reviews, 2013)
Keywords: Adult; Aged; Aged, 80 and over; betaine; Betaine - blood; Biomarkers - blood; Case-Control Studies; choline; diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - genetics; Diabetic Angiopathies - genetics; Female; Genotype; homocysteine; Homocysteine - blood; Humans; Male; microangiopathy; Middle Aged; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase - genetics; polymorphism; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; homocysteine; choline; microangiopathy; polymorphism; betaine; diabetes