Metformin improves endothelial function in type 1 diabetic subjects: a pilot, placebo-controlled randomized study - Pitocco, D.; Zaccardi, F.; Tarzia, P.; Milo, M.; Scavone, G.; Rizzo, P.; Pagliaccia, F.; Nerla, R.; Di Franco, A.; Manto, A.; Rocca, B.; Lanza, G. A.; et al. (Diabetes, obesity & metabolism, 2013)
Keywords: Adult; Biomarkers - blood; Biomarkers - metabolism; Blood Glucose - metabolism; Brachial Artery - drug effects; Brachial Artery - physiopathology; cardiovascular disease; Confidence intervals; Diabetes; diabetes complications; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - drug therapy; Diabetes Mellitus, Type 1 - physiopathology; Dinoprost - metabolism; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular - drug effects; Endothelium, Vascular - physiopathology; Female; Glycated Hemoglobin A - metabolism; Humans; Hypoglycemic Agents - therapeutic use; Insulin - therapeutic use; macrovascular disease; Male; metformin; Metformin - therapeutic use; Oxidative stress; Oxidative Stress - drug effects; Pilot Projects; Treatment Outcome; type 1 diabetes; Vasodilation - drug effects