Emergence of Copper‐Mediated Formation of C–C Bonds

Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaini...

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Published inEuropean journal of organic chemistry Vol. 2017; no. 2; pp. 209 - 228
Main Authors Maaliki, Carine, Thiery, Emilie, Thibonnet, Jérôme
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 10.01.2017
Wiley-VCH Verlag
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Abstract Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper‐mediated formation of carbon–carbon bonds illustrated by different coupling reactions: cross‐dehydrogenative coupling, decarboxylative cross‐coupling, Sonogashira‐type reactions, Suzuki‐type reactions, and Neigishi‐type reactions. Domino reactions and, finally, more atypical reactions are also illustrated. An overview of copper‐catalyzed C–C bond reactions through the main recently developed methodologies is presented.
AbstractList Copper-catalyzed cross-coupling reactions have found widespread application in carbon-carbon or carbon-heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper-mediated formation of carbon-carbon bonds illustrated by different coupling reactions: cross-dehydrogenative coupling, decarboxylative cross-coupling, Sonogashira-type reactions, Suzuki-type reactions, and Neigishi-type reactions. Domino reactions and, finally, more atypical reactions are also illustrated.
Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper‐mediated formation of carbon–carbon bonds illustrated by different coupling reactions: cross‐dehydrogenative coupling, decarboxylative cross‐coupling, Sonogashira‐type reactions, Suzuki‐type reactions, and Neigishi‐type reactions. Domino reactions and, finally, more atypical reactions are also illustrated. An overview of copper‐catalyzed C–C bond reactions through the main recently developed methodologies is presented.
Author Maaliki, Carine
Thibonnet, Jérôme
Thiery, Emilie
Author_xml – sequence: 1
  givenname: Carine
  surname: Maaliki
  fullname: Maaliki, Carine
  organization: Université François‐Rabelais
– sequence: 2
  givenname: Emilie
  surname: Thiery
  fullname: Thiery, Emilie
  email: emilie.thiery@univ‐tours.fr
  organization: Université François‐Rabelais
– sequence: 3
  givenname: Jérôme
  surname: Thibonnet
  fullname: Thibonnet, Jérôme
  email: jerome.thibonnet@univ‐tours.fr
  organization: Université François‐Rabelais
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2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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Issue 2
Keywords C-C coupling
carbon carbon bond
liaison carbone carbone
décarboxylation
déhydrogenase
domini reactions
decarboxylative coupling
dehydrogenative coupling
Copper
synthetic methods
Language English
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Snippet Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity,...
Copper-catalyzed cross-coupling reactions have found widespread application in carbon-carbon or carbon-heteroatom bond formation. The relatively low toxicity,...
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SubjectTerms Carbon
Chemical Sciences
Copper
C–C coupling
Decarboxylative coupling
Dehydrogenative coupling
Domino reactions
Organic chemistry
Synthetic methods
Title Emergence of Copper‐Mediated Formation of C–C Bonds
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fejoc.201600540
https://www.proquest.com/docview/1859418633
https://hal.science/hal-01601331
Volume 2017
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