Emergence of Copper‐Mediated Formation of C–C Bonds

Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaini...

Full description

Saved in:
Bibliographic Details
Published inEuropean journal of organic chemistry Vol. 2017; no. 2; pp. 209 - 228
Main Authors Maaliki, Carine, Thiery, Emilie, Thibonnet, Jérôme
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 10.01.2017
Wiley-VCH Verlag
Subjects
Carbon
Chemical Sciences
Copper
C–C coupling
Decarboxylative coupling
Dehydrogenative coupling
Domino reactions
Organic chemistry
Synthetic methods
C-C coupling
carbon carbon bond
liaison carbone carbone
décarboxylation
déhydrogenase
domini reactions
decarboxylative coupling
dehydrogenative coupling
Copper
synthetic methods
Online AccessGet full text

Cover

More Information
Summary:Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper‐mediated formation of carbon–carbon bonds illustrated by different coupling reactions: cross‐dehydrogenative coupling, decarboxylative cross‐coupling, Sonogashira‐type reactions, Suzuki‐type reactions, and Neigishi‐type reactions. Domino reactions and, finally, more atypical reactions are also illustrated. An overview of copper‐catalyzed C–C bond reactions through the main recently developed methodologies is presented.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201600540