Measurement of kidney perfusion by magnetic resonance imaging: comparison of MRI with arterial spin labeling to para-aminohippuric acid plasma clearance in male subjects with metabolic syndrome

• Published in: Nephrology, dialysis, transplantation Vol. 25; no. 4; pp. 1126 - 1133
• Main Authors: Ritt, Martin, Janka, Rolf, Schneider, Markus P., Martirosian, Petros, Hornegger, Joachim, Bautz, Werner, Uder, Michael, Schmieder, Roland E.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.2010
• Subjects: Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Angiotensin II Type 1 Receptor Blockers - therapeutic use; Arteries - drug effects; Benzimidazoles - therapeutic use; Benzoates - therapeutic use; Biological and medical sciences; Blood Pressure - drug effects; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Creatinine - metabolism; Emergency and intensive care: renal failure. Dialysis management; Hemodynamics; Humans; Intensive care medicine; Kidney - blood supply; kidney perfusion; magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical sciences; Metabolic Syndrome - physiopathology; Middle Aged; p-Aminohippuric Acid - blood; para-aminohippuric acid plasma clearance; Renal Circulation; renal plasma flow; Renal Plasma Flow - drug effects; Spin Labels; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Young Adult; Kidney disease; Human; magnetic resonance imaging; Urinary system disease; Hemodialysis; para-aminohippuric acid plasma clearance; Nuclear magnetic resonance imaging; renal plasma flow; Extrarenal dialysis; Perfusion imaging; Renal failure; kidney perfusion; Spin labeling; Comparative study

Background. Magnetic resonance imaging with arterial spin labeling (MRI–ASL) is a non-invasive approach to measure organ perfusion. We aimed to examine whether MRI–ASL kidney perfusion measurements are related to measurements of renal plasma flow (RPF) by para-aminohippuric acid (PAH) plasma clearan...