Lipophilic antioxidants in blood plasma as markers of atherosclerosis: the role of α-carotene and γ-tocopherol

• Published in: Atherosclerosis Vol. 144; no. 1; pp. 117 - 122
• Main Authors: Kontush, Anatol, Spranger, Torsten, Reich, Axel, Baum, Katja, Beisiegel, Ulrike
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ireland Ltd 01.05.1999; Elsevier
• Subjects: Adult; Antioxidants - analysis; Antioxidants - metabolism; Atherosclerosis; Atherosclerosis (general aspects, experimental research); beta Carotene - blood; Biological and medical sciences; Biomarkers - analysis; Blood and lymphatic vessels; Cardiology. Vascular system; Coronary Artery Disease - blood; Coronary heart disease; Female; Humans; Lipid Peroxidation; Lipoprotein oxidation; Male; Medical sciences; Middle Aged; Multivariate Analysis; Reference Values; Regression Analysis; Sensitivity and Specificity; Severity of Illness Index; Tocopherols; Ubiquinol-10; Vitamin E - blood; α-Carotene; β-Carotene; Lipoprotein oxidation; Atherosclerosis; α-Carotene; Tocopherols; Coronary heart disease; Ubiquinol-10; β-Carotene; Vascular disease; Human; Carotene; Risk factor; Cardiovascular disease; α-Tocopherol; Blood plasma

Oxidative theory of atherosclerosis implies that plasma levels of lipophilic antioxidants might serve as indicators of lipoprotein oxidation in the arterial wall and as markers of the development of atherosclerosis. However, it is unknown whether the measurement of plasma antioxidants is able to ref...