Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice - Murray, Fraser; Smith, David W.; Hutson, Peter H. (European journal of pharmacology, 2008)
Keywords: Adrenal Glands - drug effects; Adult and adolescent clinical studies; Animals; Antidepressant; Antidepressive Agents, Second-Generation - pharmacology; Antidepressive Agents, Tricyclic - pharmacology; Antimetabolites; Anxiety - psychology; Behavior, Animal - drug effects; Behaviour; Biological and medical sciences; Bromodeoxyuridine; Cell Proliferation - drug effects; Chemistry, Pharmaceutical; Corticosterone; Corticosterone - blood; Corticosterone - pharmacology; Depression; Depression - psychology; Fluoxetine - pharmacology; Glucocorticoid; Hippocampus - anatomy & histology; Hippocampus - cytology; Hippocampus - drug effects; Imipramine - pharmacology; Immunohistochemistry; Lighting; Male; Medical sciences; Mice; Mood disorders; Neurogenesis; Organ Size - drug effects; Pharmacology. Drug treatments; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Swimming - psychology; Antidepressant; Depression; Behaviour; Corticosterone; Glucocorticoid; Neurogenesis; Cell proliferation; Affect affectivity; Psychotropic; Central nervous system; Encephalon; Antidepressant agent; Anxiety; Behavior; Cell volume; Mood disorder; Steroid hormone; Low dose; Rodentia; Vertebrata; Chronic; Mammalia; Mouse; Animal; Adrenal hormone; Hippocampus