Maternal–fetal blood incompatibility and the risk of schizophrenia in offspring

• Published in: Schizophrenia research Vol. 80; no. 2-3; pp. 331 - 342
• Main Authors: Insel, Beverly J., Brown, Alan S., Bresnahan, Michaeline A., Schaefer, Catherine A., Susser, Ezra S.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 15.12.2005; Elsevier Science
• Subjects: ABO incompatibility; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Blood Group Incompatibility; Female; Humans; Male; Maternal-Fetal Exchange - physiology; Maternal–fetal blood incompatibility; Medical sciences; Pregnancy; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Rh incompatibility; Risk Factors; Schizophrenia; Schizophrenia - etiology; Schizophrenia - physiopathology; Schizophrenia spectrum disorder; Rh incompatibility; Schizophrenia; Maternal–fetal blood incompatibility; ABO incompatibility; Schizophrenia spectrum disorder; Psychosis; Human; Maternal-fetal incompatibility; Progeny; Blood group; Maternal-fetal blood incompatibility; Risk factor

Predicated on a maternal immune response to paternally inherited foreign fetal blood antigens, we hypothesized that maternal–fetal blood incompatibility increases susceptibility to schizophrenia in the offspring. The relation between schizophrenia and maternal–fetal blood incompatibility, arising fr...