H63D CG genotype of HFE is associated with increased risk of sporadic amyotrophic lateral sclerosis in a single population

• Published in: Journal of integrative neuroscience Vol. 19; no. 3; pp. 495 - 499
• Main Authors: Zhang, Qing-Qing, Jiang, Hong, Li, Chun-Yan, Liu, Ya-Ling, Tian, Xin-Ying
• Format: Journal Article
• Language: English
• Published: IMR Press 30.09.2020
• Subjects: neurogenetics|amyotrophic lateral sclerosis|motor neuron disease|hfe gene|polymorphism

This paper describes the genetic etiology of sporadic amyotrophic lateral sclerosis in a single population. Polymerase chain reaction-restriction fragment length polymorphism and DNA sample sequencing of 3 common HFE gene variants (C282Y and H63D and S65C) were performed on 10 randomly selected samp...