Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect

• Published in: Science advances Vol. 1; no. 6
• Main Authors: Karukurichi, Kannan R, Fei, Xiang, Swyka, Robert A, Broussy, Sylvain, Shen, Weijun, Dey, Sangeeta, Roy, Sandip K, Berkowitz, David B
• Format: Journal Article
• Language: English
• Published: United States American Association for the Advancement of Science 01.07.2015
• Subjects: Physical Sciences; SciAdv r-articles

This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetric synthesis. The carbafructopyranosyl-1,2-diamine(s) and salens constructed therefrom are particularly compelling. It is shown that by removing the nat...