Angiogenesis modulatory factors in subjects with chronic ocular complications of Sulfur Mustard exposure: A case-control study

• Published in: International immunopharmacology Vol. 76; p. 105843
• Main Authors: Heidary, Fatemeh, Gharebaghi, Reza, Ghasemi, Hassan, Mahdavi, Mohammad Reza Vaez, Ghaffarpour, Sara, Naghizadeh, Mohammad Mehdi, Ghazanfari, Tooba
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2019; Elsevier BV
• Subjects: Adult; Aged; Angiogenesis; Blood vessels; Case-Control Studies; Chemical Warfare Agents - toxicity; Complications; Cornea; Environmental Exposure - adverse effects; Enzyme-linked immunosorbent assay (ELISA); Exposure; Eye Injuries - blood; Eye Injuries - chemically induced; Eye Injuries - epidemiology; Growth factors; Humans; Interleukin 12; Interleukin 12 (IL-12); Interleukin 17; Interleukin 17 (IL-17); Interleukin-12 - blood; Interleukin-17 - blood; Iran - epidemiology; Male; Middle Aged; Morbidity; Mustard gas; Mustard Gas - toxicity; Neovascularization, Physiologic; Nitric oxide; Nitric oxide (NO); Nitric Oxide - blood; Serum levels; Subgroups; Sulfur; Sulfur Mustard (SM); Vascular endothelial growth factor; Vascular Endothelial Growth Factor C - blood; Vascular Endothelial Growth Factor D - blood; Vascular endothelial growth factor-C (VEGF-C); Vascular endothelial growth factor-D (VEGF-D); Young Adult; Iran; Sulfur Mustard (SM); Enzyme-linked immunosorbent assay (ELISA); Interleukin 17 (IL-17); Vascular endothelial growth factor-C (VEGF-C); Interleukin 12 (IL-12); Vascular endothelial growth factor-D (VEGF-D); Nitric oxide (NO)

Chronic ocular complications of Sulfur Mustard (SM) exposure leads to severe ocular morbidity during time. The aim of this study was to compare serum levels of Interleukin 17 (IL-17), IL-12, vascular endothelial growth factor (VEGF)-C, VEGF-D and nitric oxide (NO) in SM-exposed patients versus the c...