The characteristics of beta 2-glycoprotein I-dependent anticardiolipin antibody and blood coagulation status in subjects with classical biological false-positive syphilis reactions

• Published in: International immunopharmacology Vol. 62; pp. 132 - 138
• Main Authors: Shen, Xu, Liu, Dan, Lin, Yong, Zhu, Xiao-Zhen, Lin, Li-Rong, Tong, Man-Li, Liang, Xian-Ming, Liu, Li-Li, Yang, Tian-Ci, Niu, Jian-Jun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2018; Elsevier BV
• Subjects: Antibodies, Anticardiolipin - blood; Antiphospholipid Syndrome - blood; Antiphospholipid Syndrome - immunology; Autoantibodies - blood; beta 2-Glycoprotein I - blood; Blood coagulation; Blood Coagulation - genetics; Cardiolipin; CBFP; Coagulation; False Positive Reactions; Genetic Heterogeneity; Glycoprotein I; Glycoproteins; Humans; Immunoglobulin G - blood; Immunoglobulin M - blood; Immunoglobulins; Sexually transmitted diseases; STD; Syphilis; Syphilis - blood; Syphilis - immunology; Syphilis Serodiagnosis; β2-GPI-dependent ACA; β2-GPI-dependent ACA; Blood coagulation; CBFP; Syphilis

Anticardiolipin antibody (ACA) includes beta2-glycoprotein I-dependent (β2-GPI-dependent) and β2-GPI-independent forms. The appearance of β2-GPI-dependent ACA and its association with blood coagulation have never been investigated in subjects with classical biological false-positive syphilis reactio...