A unique dosage form to evaluate the mechanical destructive force in the gastrointestinal tract - Kamba, Masaharu; Seta, Yasuo; Kusai, Akira; Ikeda, Masaru; Nishimura, Kenji (International journal of pharmaceutics, 2000)
Keywords: Adult; Biological and medical sciences; Biomechanical Phenomena; Compressive Strength; Destructive force; Fasting - urine; Gastrointestinal Contents; Gastrointestinal Motility - physiology; Gastrointestinal transit; General pharmacology; Humans; Male; Medical sciences; Middle Aged; Particle Size; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Photosensitizing Agents - chemistry; Photosensitizing Agents - urine; Polytetrafluoroethylene - chemistry; Polytetrafluoroethylene - pharmacokinetics; Powders; Riboflavin; Riboflavin - chemistry; Riboflavin - urine; Solubility; Stomach; Tablets; Teflon; Teflon; Gastrointestinal transit; Riboflavin; Stomach; Destructive force; Structure stability; Disintegration; Hydrophobicity; Powder compact; Release; Physical structure; Human; Urine; Pharmaceutical technology; Healthy subject; Digestive system; Oral administration; Mechanical properties; Direct compression; Dissolution; In vitro; Pressure; Physical properties; In vivo; Destructive test; Dosage form; Pharmacokinetics; Physicochemical properties