Emerging microRNAs in cancer diagnosis, progression, and immune surveillance

• Published in: Cancer letters Vol. 438; pp. 126 - 132
• Main Authors: Harrandah, Amani M., Mora, Rodrigo A., Chan, Edward K.L.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.12.2018; Elsevier Limited
• Subjects: Biomarkers; Biosynthesis; Cancer; Cancer immunity; Cancer therapies; Cell cycle; Diagnosis; Esophagus; Gastric cancer; Gene expression; Gene loci; Gene regulation; Genetic engineering; Genomes; Immunology; Immunosurveillance; Immunotherapy; Leukemia; Lung cancer; Lymphoma; Medical diagnosis; Medical prognosis; MicroRNAs; miR-21; miR-375; miRNA; oncomiR; Oral cancer; Post-transcription; Prognostic biomarker; Proteins; RAS pathway; RNA polymerase; Tumors; IFN-ɣ; SPRY; PTEN; MHC; pre-miRNAs; pri-miRNAs; MTDH; UTR; PI3K; FFPE; miRNA; miR-21; JAK2; RAS pathway; Prognostic biomarker; PDK1; OSCC; oncomiR; MMPs; AKT; CIP2A; TCGA; RHOB; MEK; ZEB1; Cancer immunity; miR-375; PDCD4; HNC; PDL1; RECK; ERK

MicroRNAs (miRNAs) are small noncoding RNAs that function in post-transcriptional regulation of gene expression. Dysregulation of miRNAs has been reported in different stages of cancer development and progression. This dysregulation results in different miRNA profiles between cancer and normal tissu...